Adriana Martínez-Cuazitl, Research Department, Hospital Central Militar; Laboratory of Cell and Tissue Biology, Escuela Militar de Medicina. Secretaría de la Defensa Nacional, Mexico City, Mexico
Eira Cerda-Reyes, Research Department, Hospital Central Militar, Secretaría de la Defensa Nacional, Mexico City, Mexico
Juan S. García-Hernández, Research Department, Hospital Central Militar, Secretaría de la Defensa Nacional, Mexico City, Mexico
Stefanny Cornejo-Hernández, Research Department, Hospital Central Militar, Secretaría de la Defensa Nacional, Mexico City, Mexico
Esly Esquivel-Alarcón, Research Department, Hospital Central Militar, Secretaría de la Defensa Nacional, Mexico City, Mexico
Ilse Y. Uriarte Sánchez, Research Department, Hospital Central Militar, Secretaría de la Defensa Nacional, Mexico City, Mexico
Mayra G. García-Araiza, Research Department, Hospital Central Militar, Secretaría de la Defensa Nacional, Mexico City, Mexico
Background: Vaccines against SARS-CoV-2 were limited, and the recommended schedule was not available. Thus, government politics covered most of the at-risk population. Objectives: Analyzed the effectiveness on mortality of unvaccinated and vaccinated patients with any kind of schedule. Methods: This retrospective study included all confirmed COVID-19 hospitalized patients at a third-level hospital in Mexico City between October 2021 and February 2023. We analyzed the risk factors and number of vaccines, the types of vaccines and their effect on death, descriptive statistics, and U–Mann–Whitney, or X2. We also have multiple logistic regressions for dead. Results: We included 567 patients; the risk factors for death were still male, age > 60, and unvaccinated, more so than any vaccine, and any kind of scheduled vaccination was better than unvaccinated. The regression showed that age, vaccination, SO2, and N/L index were the main factors that predicted death. Conclusions: Vaccinated patients with any schedule, with at least one dose of vaccine, could be the better option at the beginning. Nowadays, it is important to administer booster shots.
Keywords: COVID-19 vaccination. Effects on survived by mixed vaccines. Vaccination strategy in Mexico.
